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'Adjuvants are, by definition, toxic. That’s why they’re used. The immune system sees a threat and acts on it. The only vaccines that don’t have adjuvants are ones that use live viruses, which carry their own risks, not to mention being particularly difficult and expensive to manufacture.
Most new vaccines utilize recombinant DNA to simulate bits of the surface of disease organisms, but these are weak antigens .They simply don’t cause enough of an immune response to create antibodies, which are the goal of vaccines. The problem is that adjuvants are also risky, possibly even more so than the antigens.'
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