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Wonderful World of Bicarbonate and CO2

 Description: Diagram of the CO2/bicarbonate physiological buffering system, showing equilibria, Ka values, and comments


'Dr Alina Vasiljeva and Dr David Nias wrote, “At the end of the 19th century, scientists Bohr and Verigo discovered what seemed a strange law: a decreased level of carbon dioxide in the blood leads to decreased oxygen supply to the cells in the body including the brain, heart, kidneys etc. 

Carbon dioxide (CO2) was found to be responsible for the bond between oxygen and haemoglobin. If the level of carbon dioxide in the blood is lower than normal, then this leads to difficulties in releasing oxygen from haemoglobin. Hence the Verigo-Bohr law.”'

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